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Inactivation of 5-HT1A receptors in hippocampal and cortical homogenates

✍ Scribed by Richard H Alper; David L Nelson

Book ID: 114012813
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 238 KB
Volume: 390
Category: Article
ISSN: 0014-2999
DOI: 10.1016/s0014-2999(00)00032-7

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## Abstract We have studied the effects of 5‐HT~1A~ and 5‐HT~7~ serotonin receptor activation in hippocampal CA3‐CA1 synaptic transmission using patch clamp on mouse brain slices. Application of either 5‐HT or 8‐OH DPAT, a mixed 5‐HT~1A~/5‐HT~7~ receptor agonist, inhibited AMPA receptor‐mediated ex