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Inactivation by the mitotic inhibitor NY 3170 of human cells in vitro

✍ Scribed by Wibe, E; Oftebro, R


Book ID
109834877
Publisher
Nature Publishing Group
Year
1979
Tongue
English
Weight
771 KB
Volume
40
Category
Article
ISSN
0007-0920

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The effect of the two closely related drugs, the sulfone 2-(2-thenyl)sulfonyl-5-bromopyrimidine (NY 4137), and the sulfoxide 2-(2-thenyl)sulfinyl-5-bromopyrimidine (NY 4138), a sulfoxide, on the survival of cells of the human line NHIK 3025 was investigated. Cell survival was measured as the ability

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## Abstract This study attempted to investigate whether different levels of mitotic activity exist within different physical regions of a human embryonic stem (hES) cell colony. Incorporation of 5‐bromo‐2‐deoxyuridine (BrdU) within newly‐synthesized DNA, followed by immunocytochemical staining was