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In vivoAntitumor Mechanism of Natural Human Tumor Necrosis Factor Involving a T Cell-mediated Immunological Route

✍ Scribed by Asami, Tetsuya ;Imai, Meroni ;Tanaka, Yasuo ;Hosaka, Yoshitaka ;Kato, Kazuharu ;Nakamura, Norio ;Horisawa, Yoshifumi ;Ashida, Yoshikazu ;Kanamori, Toshinori ;Nobuhara, Masahiro ;Kurimoto, Masashi


Book ID
108578795
Publisher
Wiley (Blackwell Publishing)
Year
1989
Tongue
English
Weight
220 KB
Volume
80
Category
Article
ISSN
0910-5050

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The role of an immune response in recombinant-human-tumor-necrosis-factor(rHTNF)-mediated regression of a weakly immunogenic, MCA-106 sarcoma in vivo was examined. C57BL/6 mice bearing established 10-day s.c. tumor were treated with single i.v. doses (8 p~g) of rHTNF, rHTNF administration resulted i