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In vivo1H chemical shift imaging of silicone implants

✍ Scribed by Bettina Pfleidere; Jerome L. Ackerman; Leoncio Garrido

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 444 KB
Volume: 29
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910290512

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

In order to study the aging process (i.e., silicone migration, fat infiltration) of silicone (polydimethylsiloxane, PDMS) based biomaterials in living subjects by NMR imaging a hybrid ^1^H selective excitation and saturation chemical shift imaging technique (IR/CHESS‐CSSE) has been developed. This sequence allows selective mapping of the distribution of silicone protons in vivo, while suppressing the contributions of fat and water. Our results indicate that a combined inversion recovery and CHESS pulse, followed by a spoiler gradient, must be applied to suppress all contributions of fat protons to the NMR signal. The sensitivity of our experiments allows the detection of a chemically unchanged silicone concentration of 5% in a voxel of 0.9 mm^3^ at a signal/noise ratio of 2.

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