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In vivo tissue reactivity of radiation-cured silicone rubber implants

✍ Scribed by Gifford, George H. ;Merrill, Edward W. ;Morgan, Michael S.

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
431 KB
Volume
10
Category
Article
ISSN
0021-9304

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✦ Synopsis

Abstract

Silicone rubber implants are clinically used in large numbers and elicit a mild tissue reaction. An occasional patient develops an accentuated reaction, an observation which has stimulated clinicians to try to understand this process more fully. The chemistry of medical silicone implants, including quantitative composition, is reviewed. This in vitro laboratory study show less tissue reaction from radiation‐cured pure silicone polymer, as compared with radiation‐cured silicone with SiO~2~ filler. A proposed system for fabrication and curing of a silicone implant, with the qualities of strength and diminished tissue reactivity, is discussed.

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