In vivo steroid regulation of aromatase and 5α-reductase in goldfish brain and pituitary
✍ Scribed by Metsada Pasmanik; Barney A. Schlinger; Gloria V. Callard
- Book ID
- 113159041
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 689 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0016-6480
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In numerous vertebrate species including Japanese quail ( C e turnix coturnix japonica), actions of testosterone (T) on neuroendocrine target tissues are mediated in part by conversion to estrogenic and androgenic metabolites. In order to assess which pathways were favored in each identified androge
## Abstract Testosterone (T) plays an important role in developing brain, dictating sex‐specific behavior and physiology. 3α,5α‐Reduced neurosteroids also regulate reproductive behavior. The key enzyme in the biosynthesis of these neurosteroids is 5α‐reductase (5α‐R), expressed as two isozymes, 5α‐