In vivo selection of retrovirally transduced hematopoietic stem cells
β Scribed by Allay, James A.; Persons, Derek A.; Galipeau, Jacques; Riberdy, Janice M.; Ashmun, Richard A.; Blakley, Raymond L.; Sorrentino, Brian P.
- Book ID
- 109702370
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 261 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1078-8956
- DOI
- 10.1038/2632
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## Abstract ## Background Hematopoietic stemβcellβdirected gene transfer has achieved limited success in transducing clinically relevant levels of target cells. The expansion of geneβmodified cells is one way to circumvent the problem of inefficient transduction with current vectors. To this end,