In vivo response of mouse lymphocytes to phytohemagglutinin and colchicine
β Scribed by Duncan A. Killen
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 247 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
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## Abstract Lymphocyte proliferation in response to mitogens, phytohemagglutinin (PHA), concanavalin A, pokeweed, and/or specific antigens has been the method of choice for in vitro diagnosis of cellβmediated immune dysfunction. Recently, an assay to measure intracellular adenosine triphosphate (AT
T h e in vitro peripheral lymphocyte response to phytohemagglutinin (PHA) was correlated with the clinical and immunologic status in 44 patients with chronic lymphocytic leukemia. T h e mean lymphocyte response was only slightly below the normal range a t day 3 of culture in patients in remission;