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In vivo quantification of monoamine oxidase A in baboon brain: a PET study using [11C]befloxatone and the multi-injection approach

✍ Scribed by Bottlaender, Michel; Valette, Héric; Delforge, Jacques; Saba, Wadad; Guenther, Ilonka; Curet, Olivier; George, Pascal; Dollé, Frédéric; Grégoire, Marie-Claude


Book ID
109871282
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
464 KB
Volume
30
Category
Article
ISSN
0271-678X

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Efficient synthesis of [11C]befloxatone,
✍ F. Dollé; Y. Bramoullé; F. Hinnen; S. Demphel; P. George; M. Bottlaender 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 110 KB

## Abstract Carbon‐11 labelled befloxatone ((5R)‐5‐(methoxymethyl)‐3‐[4‐[(3R)‐4,4,4‐trifluoro‐3‐hydroxybutoxy]phenyl]‐2‐oxazolidinone) is a reversible and selective monoamine oxidase‐A (MAO‐A) inhibitor and appears to be a new potent PET tracer for the __in vivo__ imaging of MAO‐A density. In this