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In vivo proton spin-lattice relaxation times of normal and dystrophic muscles

✍ Scribed by P. A. Narayana; W. W. Brey; M. V. Kulkarni; L. K. Misra

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
524 KB
Volume
4
Category
Article
ISSN
0740-3194

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✦ Synopsis

In vivo spin-lattice relaxation times (TI) of water and lipid protons were measured in normal and dystrophic chicken pectoralis muscles at different ages. Values were obtained with a surface coil used as both a receiver and a transmitter. A 28-TI-8-Acquisition sequence was used for these measurments. Accuracy was verified with an inversion-recovery method using a slotted tube resonator as the transmitter and a surface coil as the receiver. It was observed that (1) the TI values of water protons in normal muscles decrease with age, (2) the TI values of water protons do not change with age in dystrophic muscles, and (3) the T, values of lipid protons increase with age in normal and dystrophic muscles. These results indicate a failure of the normal maturation of dystrophic muscles.

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