## Abstract A methodological development for quantitative shortβechoβtime (TE) in vivo proton MR spectroscopy (MRS) without water suppression (WS) is described that integrates experimental and software approaches. Experimental approaches were used to eliminate frequency modulation sidebands and fir
In vivo proton spectroscopy without solvent suppression
β Scribed by Clayton, David B. ;Elliott, Mark A. ;Lenkinski, Robert E.
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 364 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1043-7347
- DOI
- 10.1002/cmr.1013
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A method is introduced for obtaining proton spectra in vivo with all the advantages of a full water signal. The method, based on F1 oversampled J-resolved spectroscopy, makes it possible to separate metabolite signals from unwanted baseline artifacts. The dominant water resonance is used as a 2D ref
## While most proton ( 1 H) spectra acquired in vivo utilize selective suppression of the solvent signal for more sensitive detection of signals from the dilute metabolites, recent reports have demonstrated the feasibility and advantages of collecting in vivo data without solvent attenuation. When