✦ LIBER ✦
Proton spectroscopy without water suppression: The oversampled J-resolved experiment
✍ Scribed by Ralph E. Hurd; David Gurr; Napapon Sailasuta
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 480 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
A method is introduced for obtaining proton spectra in vivo with all the advantages of a full water signal. The method, based on F1 oversampled J-resolved spectroscopy, makes it possible to separate metabolite signals from unwanted baseline artifacts. The dominant water resonance is used as a 2D reference signal for the phase-sensitive reconstruction of the 2D J-resolved metabolite spectra. The powerful specificity of this method is demonstrated with model compound spectra, phantoms, and in vivo examples.