Detection of β-thalassemia and hemoglobi
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Pranee Winichagoon; Jiraporn Kownkon; Pathai Yenchitsomanus; Varaporn Thonglairo
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Article
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1989
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Springer
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English
⚖ 222 KB
Enzymatic DNA amplification and polyacrylamide gel electrophoresis, which demonstrate different sizes of DNA fragments, were used to detect the common mutations causing beta-thalassemia and hemoglobin (Hb) E in Thai people. The 4-bp deletion at codons 41 and 42 can be detected directly by polyacryla