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In vivo Platelet Activation and Hyperaggregation in Hemoglobin E/β-Thalassemia: A Consequence of Splenectomy

✍ Scribed by Vichai Atichartakarn; Pantep Angchaisuksiri; Katcharin Aryurachai; Suporn Chuncharunee; Ammarin Thakkinstian


Publisher
Carden Jennings Publishing
Year
2003
Tongue
English
Weight
79 KB
Volume
77
Category
Article
ISSN
0925-5710

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Detection of β-thalassemia and hemoglobi
✍ Pranee Winichagoon; Jiraporn Kownkon; Pathai Yenchitsomanus; Varaporn Thonglairo 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 222 KB

Enzymatic DNA amplification and polyacrylamide gel electrophoresis, which demonstrate different sizes of DNA fragments, were used to detect the common mutations causing beta-thalassemia and hemoglobin (Hb) E in Thai people. The 4-bp deletion at codons 41 and 42 can be detected directly by polyacryla