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In-vivo PET detection of neurodegenerative pathologies in a transgenic mouse model of tauopathies

✍ Scribed by Satoko Hattori; Masahiro Maruyama; Chie Seki; Bin Ji; Jun Maeda; Takashi Okauchi; Misao Yoneyama; Shigeyoshi Saito; Ichio Aoki; Makoto Higuchi; Tetsuya Suhara

Book ID: 116776941
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 97 KB
Volume: 65
Category: Article
ISSN: 0168-0102
DOI: 10.1016/j.neures.2009.09.544

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## Abstract The present study was undertaken to investigate whether chronic endurance exercise affects tau phosphorylation levels in the brain with Alzheimer's disease (AD)‐like pathology. To address this, the transgenic (Tg) mouse model of tauopathies, Tg‐__NSE/htau23,__ which expresses human tau2