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In vivo neutralization of hepatitis B virus infection by an anti-preS1 humanized antibody in chimpanzees

✍ Scribed by Hyo Jeong Hong; Chun Jeih Ryu; Hyangsuk Hur; Seho Kim; Han Kyu Oh; Mee Sook Oh; Song Yong Park


Book ID
113945724
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
313 KB
Volume
318
Category
Article
ISSN
0042-6822

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## Abstract Two study chimpanzees were inoculated intravenously with approximately 1,000 chimpanzee infectious doses of hepatitis B virus (HBV), one with subtype adr and one with subtype ayw, each previously incubated with 0.1 ml of a murine monoclonal antibody (IgG ~1(K)~ class) directed against a