Acetylation and pentafluorobenzoylation
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R. T. Coutts; G. A. Torok-Both; Y. K. Tam; L. V. Chu; F. M. Pasutto
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Article
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1987
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John Wiley and Sons
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English
β 613 KB
Known and possible phenolic and primary and secondary amine metabolites of lidocaine were added to urine from drug-naive rats. These metabolites were derivatized in this aqueous medium by acetylation with acetic anhydride or by pentafluorobenzoylation with pentafluorobenzoyl chloride. The derivative