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In vivo inactivation of phosphotyrosine protein phosphatases by nitric oxide

✍ Scribed by Anna Caselli; Paola Chiarugi; Guido Camici; Giampaolo Manao; Giampietro Ramponi


Book ID
115931455
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
373 KB
Volume
374
Category
Article
ISSN
0014-5793

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We investigated the mechanism of nitric oxide (NO) action on hepatic methionine adenosyltransferase (MAT) activity using S-nitrosoglutathione (GSNO) as NO donor. Hepatic MAT plays an essential role in the metabolism of methionine, converting this amino acid into S-adenosylmethionine. Hepatic MAT exi