Activation of osteoclasts by interleukin
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S.W. Fox; K. Fuller; T.J. Chambers
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Article
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2000
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John Wiley and Sons
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English
โ 254 KB
๐ 1 views
Recently, it has been found that osteoclasts are induced and activated by osteoblastic cells through expression of receptor activator NF-kB ligand (RANKL), and that soluble recombinant RANKL, with M-CSF, can replace the need for osteoblastic cells in osteoclast formation. We exploited this opportuni