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In vivo gene expression: combining hydrodynamics-based transfection and electrotransfer

✍ Scribed by Justin Teissié

Book ID
114152600
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
33 KB
Volume
20
Category
Article
ISSN
0167-7799

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## Abstract ## Background Rapid intravenous injection of a large volume of plasmid DNA (pDNA), i.e. a transfection procedure based on hydrodynamics, is known to be an efficient and liver‐specific method of __in vivo__ gene delivery. However, the gene expression is transient. ## Methods We invest