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In vivo GABA detection with improved selectivity and sensitivity by localized double quantum filter technique at 4.1T

✍ Scribed by Fei Du; Wen-Jang Chu; Baolian Yang; Jan A. Den Hollander; Thian C. Ng

Book ID
103840065
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
122 KB
Volume
22
Category
Article
ISSN
0730-725X

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## Abstract A proton MR spectral editing technique employing a spatially localized, double‐quantum filter (DQF) was used to measure γ‐aminobutyric acid (GABA) in the human brain at 1.5 T. The double‐quantum method provided robust, single‐shot suppression of uncoupled resonances from choline, creati