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In vivo evidence for a regulatory role of the kinase activity of thelinotte/derailedreceptor tyrosine kinase, aDrosophilaRyk ortholog

✍ Scribed by Emmanuel Taillebourg; Caroline Moreau-Fauvarque; Katia Delaval; Jean-Maurice Dura


Book ID
106116077
Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
223 KB
Volume
215
Category
Article
ISSN
0949-944X

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Phosphotyrosine (P-Tyr) antibodies have been used to identify the phosphorylated forms of growth factor receptors and oncogene-coded tyrosine kinases. Western blot analysis of a gastric carcinoma cell line with P-Tyr antibodies revealed a tyrosine-phosphorylated protein of M, 145,000 (P145). In addi