## Abstract This work reports the synthesis, radiolabelling and __in vivo__ evaluation in NMRI mice of [^123^I]β(4βfluorophenyl)[1β(3βiodophenethyl)piperidinβ4βyl]methanone ([^123^I]β3βIβCO) as a potential SPECT tracer for the 5βHT~2A~ receptor. The tributylstannylprecursor was synthesized with a 1
β¦ LIBER β¦
In vivo evaluation in rodents of [123I]-3-I-CO as a potential SPECT tracer for the serotonin 5-HT2A receptor
β Scribed by Peter B.M. Blanckaert; Ingrid Burvenich; Leonie Wyffels; Sylvie De Bruyne; Lieselotte Moerman; Filip De Vos
- Book ID
- 116799261
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 258 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0969-8051
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## Abstract Many people suffer from psychiatric illnesses like depression and anorexia. Relevant to these diseases is amongst others a malfunctioning of brain 5βHT~2A~βreceptors. To allow __in vivo__ quantification of these receptors with Single Photon Emission Computerized Tomography (SPECT), a ra