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In vivo electrophysiological and neurochemical effects of the selective 5-HT1Areceptor agonist, F13640, at pre- and postsynaptic 5-HT1Areceptors in the rat

✍ Scribed by Laia Lladó-Pelfort; Marie-Bernadette Assié; Adrian Newman-Tancredi; Francesc Artigas; Pau Celada

Book ID
113021602
Publisher
Springer
Year
2011
Tongue
English
Weight
292 KB
Volume
221
Category
Article
ISSN
0033-3158

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✍ Lynne E. Rueter; Claude De Montigny; Pierre Blier 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 251 KB 👁 1 views

Flibanserin (BIMT 17) has been described as a 5-HT 1A agonist with preferential affinity for postsynaptic 5-HT 1A receptors and as a 5-HT 2A antagonist. Indeed, using the forskolin-stimulated cAMP accumulation technique, flibanserin but not the 5-HT 1A agonists buspirone and 8-OH-DPAT had agonistic