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Interaction of the novel antipsychotic aripiprazole with 5-HT1Aand 5-HT2Areceptors: functional receptor-binding and in vivo electrophysiological studies

✍ Scribed by Arlene D. Stark; Shaun Jordan; Kelly A. Allers; Robert L. Bertekap; Ruoyan Chen; Tanaz Mistry Kannan; Thaddeus F. Molski; Frank D. Yocca; Trevor Sharp; Tetsuro Kikuchi; Kevin D. Burris

Publisher
Springer
Year
2006
Tongue
English
Weight
276 KB
Volume
190
Category
Article
ISSN
0033-3158

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## Abstract In this study, we examined the interaction of 5‐HT~1A~ and 5‐HT~2A~ receptors in the rat medial prefrontal cortex (mPFc) using the techniques of extracellular single unit recording and microiontophoresis. The iontophoresis of the selective 5‐HT~1A~ receptor agonist (Β±)‐8‐hydroxy‐2‐(di‐n