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In vivo effects of vanadium in diabetic rats are independent of changes in PI‐3 kinase activity in skeletal muscle

✍ Scribed by Askar Mohammad; Sanjay Bhanot; John H. McNeill

Book ID: 110366888
Publisher: Springer
Year: 2001
Tongue: English
Weight: 72 KB
Volume: 223
Category: Article
ISSN: 0300-8177
DOI: 10.1023/a:1017913130401

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## Abstract Guanosine has many trophic effects in the CNS, including the stimulation of neurotrophic factor synthesis and release by astrocytes, which protect neurons against excitotoxic death. Therefore, we questioned whether guanosine protected astrocytes against apoptosis induced by staurosporin