## Abstract Phosphatidylinositol 3‐kinase (PI3K)/Akt and nuclear factor‐kappa B (NF‐κB) signaling pathways play a critical role in mediating survival signals. In this study we have investigated how loss of dystrophin (the primary cause of Duchenne muscular dystrophy) modulates the activation of PI3
✦ LIBER ✦
Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action
✍ Scribed by M. Friedrichsen; P. Poulsen; E. A. Richter; B. F. Hansen; J. B. Birk; R. Ribel-Madsen; K. Stender-Petersen; E. Nilsson; H. Beck-Nielsen; A. Vaag; J. F. P. Wojtaszewski
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 260 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Regulation of phosphatidylinositol 3-kin
✍
Charu Dogra; Harish Changotra; Jon E. Wergedal; Ashok Kumar
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 472 KB
Effects of small molecule inhibitors of
✍
Lova Segerström; Ninib Baryawno; Baldur Sveinbjörnsson; Malin Wickström; Lotta E
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
French
⚖ 691 KB
## Abstract Activation of the PI3K/Akt signaling pathway is correlated with poor prognosis in neuroblastoma, the most common and deadly extracranial tumor of childhood. In this study, we show that the small‐molecule inhibitors of phosphoinositide‐dependent protein kinase‐1 (PDK1) OSU03012 and the d