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In vivo diffusion weighted 19F MRI using SF6

✍ Scribed by José M. Pérez-Sánchez; Rigoberto Pérez de Alejo; Ignacio Rodríguez; Manuel Cortijo; Germán Peces-Barba; Jesús Ruiz-Cabello

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
227 KB
Volume
54
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Diffusion weighted ^19^F images of rat lung in vivo using SF~6~ are presented. Projection‐reconstruction images were acquired by filling the rat lung with a mixture of SF~6~ and air, during 64 successive apneas. Each apnea lasted for 6 s, the time required to perform 100 accumulations of each k‐space radial phase step for the five values of the diffusion gradient (TR = 10 ms). After diffusion images were acquired, an apparent diffusion coefficient (ADC) map was generated, yielding an average value for the ADC of 2.22 × 10^‐6^ m^2^/s and SD for ADC values of 1.27 × 10^‐6^ m^2^/s. To the best of our knowledge, this is the first in vivo diffusion weighting imaging application and the first ADC map obtained using ^19^F MRI. Magn Reson Med 54:460–463, 2005. © 2005 Wiley‐Liss, Inc.

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