Mechanisms of cytotoxicity induced by ho
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Olga Greco; Gabi U. Dachs; Gillian M. Tozer; Chryso Kanthou
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Article
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2002
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John Wiley and Sons
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English
โ 270 KB
We have previously proposed the horseradish peroxidase (HRP) and the non-toxic plant hormone indole-3-acetic acid (IAA) as a novel system for gene-directed enzyme/prodrug therapy (GDEPT). The cytotoxic potential of HRP/IAA GDEPT and the induction of a bystander effect were demonstrated in vitro unde