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In vivo assessment of hepatic and extrahepatic first pass effect of salbutamol (SALB) in anesthetized rabbits

โœ Scribed by S. Perreault; L. Dumont; H. Ong; P. du Souich


Book ID
115885078
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
201 KB
Volume
183
Category
Article
ISSN
0014-2999

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Studies were designed to allow an in vivo estimation of the hepatic extraction ratio and to test the hypothesis that the pharmacokinetic parameters of (-)-CBV are significantly different during anesthesia. (-)-CBV was administered as an IV bolus followed by IV infusion into either the portal (n = 3)