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In vivo and in vitro studies on effects of amyloid-β on the transcription factor C/EBPδ

✍ Scribed by Linda Tracy; Veronica Ramberg; Malin Samuelsson; Lars Nilsson; Kerstin Iverfeldt


Book ID
118466641
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
48 KB
Volume
6
Category
Article
ISSN
1552-5260

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The transcription factors CCAAT/enhancer binding protein (C/EBP)-␤ and -␦ are key regulators for the expression of the acute phase genes in the liver, such as complement component C3 and antichymotrypsin. In the brain, these acute phase proteins are produced in response to pro-inflammatory cytokines