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In vivo and in vitro effect of phenytoin on rat hepatic mixed function oxidases

โœ Scribed by Kanchan Srivastava; Jayanti P. Barthwal; Prahlad K. Seth


Book ID
115781370
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
462 KB
Volume
39
Category
Article
ISSN
0006-2952

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โœ Sun-Mee Lee; Mark G. Clemens ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 716 KB

This study was done to determine the relationship between microsomal lipid peroxidation during hepatic ischemia/reperfusion and alteration in cytochrome P-450-dependent drug metabolism. Rats were pretreated with a-tocopherol to inhibit lipid peroxidation or with vehicle (soybean oil) and then subjec