Effect of mirex on the activities of various rat hepatic mixed-function oxidases
โ Scribed by H. M. Mehendale; P. R. Chen; L. Fishbein; H. B. Matthews
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 616 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0090-4341
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๐ SIMILAR VOLUMES
This study was done to determine the relationship between microsomal lipid peroxidation during hepatic ischemia/reperfusion and alteration in cytochrome P-450-dependent drug metabolism. Rats were pretreated with a-tocopherol to inhibit lipid peroxidation or with vehicle (soybean oil) and then subjec
A drastic impairment in hepatic mixed-function oxidase (MFO) system was observed in rats 24 h following ip injection of CCl 4 (1.0 ml/kg body weight), as indicated by a decrease in the activities of various microsomal enzymes related to drug metabolism (e.g., aniline hydroxylase, aminopyrine-Ndemeth