## Abstract In vivo ^1^H NMR spectra from the human brain were measured at 7 T. Ultrashort echo‐time STEAM was used to minimize J‐modulation and signal attenuation caused by the shorter __T__~2~ of metabolites. Precise adjustment of higher‐order shims, which was achieved with FASTMAP, was crucial t
In vivo 1H NMR spectroscopy of individual human brain metabolites at moderate field strengths
✍ Scribed by Andreas H. Trabesinger; Dieter Meier; Peter Boesiger
- Book ID
- 108213493
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 143 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0730-725X
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## Abstract Localized __in vivo__ proton NMR spectra of volume elements of minimal size (13 × 13 × 13 mm^3^) were obtained in human brain with a whole‐body imager working at 1.5‐T field strength. By use of an optimized version of the 90°‐180°‐180° volume selection method, well‐resolved proton spect
At the high field strength of 7 T, __in vivo__ spectra of the human brain with exceptional spectral quality sufficient to quantify 16 metabolites have been obtained previously only in the occipital lobe. However, neurochemical abnormalities associated with many brain disorders are expected to occur