In Vivo 1H Magnetic Resonance Spectroscopic Measurement of Brain Glycine Levels in Nonketotic Hyperglycinemia
β Scribed by Lidia Gabis; Patricia Parton; Patricia Roche; Nicholas Lenn; Alina Tudorica; Wei Huang
- Book ID
- 109266748
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 70 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1051-2284
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A singleβvoxel proton magnetic resonance spectroscopy (^1^HβMRS) method is described that enables the in vivo measurement of endogenous brain glycine (Gly) levels in human subjects. At 4.0 T, TEβaveraging ^1^HβMRS dramatically attenuates the overlapping __myo__βinositol (mI) resonances
## Abstract A new ^1^HβMRS filtering strategy for selective measurement of glycine (Gly) in human brain in vivo at 3.0T is proposed. Investigation of multiple refocusing following a 90Β° excitation pulse indicated that triple refocusing is most effective for suppression of the strongly coupled reson