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In vitrostudy of rat prostate 5α-reductase activity and its inhibition

✍ Scribed by I. Faredin; I. Tóth; J. Oszlánczy; S. Scultéty


Book ID
110552607
Publisher
Springer Netherlands
Year
1992
Tongue
English
Weight
482 KB
Volume
24
Category
Article
ISSN
0301-1623

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BACKGROUND. Steroid 5a-reductase is essential for the intracellular accumulation of dihydrotestosterone (DHT), which mediates androgen effects on target tissue. METHODS. In the present study, we describe the differential expression and cellular localization of 5a-reductase 1 and 2 isoenzymes in the