Extracts from fruits of Sabal serrulata are used in the treatment of human benign prostatic hyperplasia (BPH). Therefore, it is of interest whether this phytopharmacon has any influence on the androgen metabolism in the human prostate. It was found that the extract IDS 89 of Sabal serrulata inhibite
Dihydrotestosterone and the concept of 5α-reductase inhibition in human benign prostatic hyperplasia
✍ Scribed by G. Bartsch; R. Rittmaster; H. Klocker
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 239 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0724-4983
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The development of treatment forms for bladder outflow obstruction resulting from benign prostatic hyperplasia is traced from the early surgical techniques to the present. The positive effects and the drawbacks of modern pharmacological treatment are weighed against each other. John Hunter, the fat
BACKGROUND. Prostate trophism depends on DHT formed from T by the enzyme 5␣-R. Two 5␣-R isoforms with different biochemical characteristics have been cloned. Also estrogens might contribute to the prostate growth; however, their intraglandular formation by the enzyme aromatase is still debated. The
In benign hyperplasia marked beta-glucuronidase and N-acetyl-beta-glucosaminidase activity was seen in the prostatic epithelium whereas the reactions for 5 other glycosidases were only slight or negative. The intensity of the reaction for the glycosidases in prostatic carcinoma was dependent upon th