A case study on the in silico absorption
✍
Ivana Kocic; Irena Homsek; Mirjana Dacevic; Sandra Grbic; Jelena Parojcic; Katar
📂
Article
📅
2012
🏛
John Wiley and Sons
🌐
English
⚖ 388 KB
👁 2 views
## ABSTRACT The aim of this case study was to develop a drug‐specific absorption model for levothyroxine (LT4) using mechanistic gastrointestinal simulation technology (GIST) implemented in the GastroPlus™ software package. The required input parameters were determined experimentally, __in silico__