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In vitroeffects of topotecan and ionizing radiation on TRAIL/Apo2L-mediated apoptosis in malignant glioma

✍ Scribed by Emilio Ciusani; Danilo Croci; Maurizio Gelati; Chiara Calatozzolo; Francesca Sciacca; Luisa Fumagalli; Marco Balzarotti; Laura Fariselli; Amerigo Boiardi; Andrea Salmaggi


Book ID
106480279
Publisher
Springer US
Year
2005
Tongue
English
Weight
394 KB
Volume
71
Category
Article
ISSN
0167-594X

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Enhancement of TRAIL/Apo2L-mediated apop
✍ Xiu-Xian Wu; Yoshiyuki Kakehi; Youichi Mizutani; Hiroyuki Nishiyama; Toshiyuki K πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 639 KB

## Abstract Renal cell carcinoma (RCC) is one of the most drug‐resistant malignancies in humans. We show that adriamycin (ADR) and TNF‐related apoptosis‐inducing ligand (TRAIL)/Apo2L have a synergistic cytotoxic effect against RCC cells. This synergistic cytotoxicity was obtained in ACHN, A704, Cak