In VitroBiotransformation of Amitriptyline and Imipramine with Rat Hepatic S9 Fraction: Evaluation of the Toxicity with Spirotox and Thamnotoxkit F™ Tests

Evaluation of 31P NMR spectroscopy as an

Evaluation of 31P NMR spectroscopy as an indicator of chemically induced hepatic toxicity in the rat: Comparison with serum enzyme levels and pathology

✍ G. S. Sandhu; N. C. Gonnella; J. C. Kapeghian; A. F. Plocinski; J. Plutchok; M. 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

Tbe pmgresion of carbon tetrachloride-induced liver damage, determined by "P NMR spectroscopy, was compared with selected serum enzyme and btollogiepI changes in rats. ATP levels declined as early 88 8 h pOst-CQ addahtm tion, with partial recovery observed at l a b . Tbe results show that ATP r e d