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In Vitro Verification of Antithrombotic Effect of Recombinant Soluble Nucleotide Triphosphate Diphosphohydrolase 1

โœ Scribed by Sampram, Ellis S.K.; Ouriel, Kenneth


Book ID
122014937
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
251 KB
Volume
15
Category
Article
ISSN
1051-0443

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## Abstract We examined the antithrombotic effect of recombinant human soluble thrombomodulin (rhsโ€TM) using an arteriovenous shunt thrombosis model and its influence on hemostasis in rats. Intravenous administration of rhsโ€TM (0.5โ€“4 mg/kg) significantly inhibited thrombus formation and prolonged e