Ectopic production of placental proteins by a variety of nontrophoblastic epithetial tumors is well recognized. Pregnancy-specific beta-1 glycoprotein (SP-I), a recently described placental protein, has been detected both in the serum and tumors of patients with breast carcinoma. To assess the sign
In vitro translation of human placental pregnancy-specific beta1-glycoprotein (SP1)
β Scribed by W. Hirunyavasit; T. Kusamran
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 227 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1420-682X
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We examined the presence of human chorionic gonadotropin (HCG) in 16 low-grade and 47 high-grade urothelial neoplasms, including two cases with trophoblastic-like differentiation. In HCG-positive tumors, the presence of human placental lactogen (HPL) and pregnancy-specific beta-1-glycoprotein (SP-1)
## Abstract Maternal serum pregnancy specific betaβ1 glycoprotein (SPβ1) levels in the second trimester may be predictive of Down syndrome (DS). An enzyme immunoassay was used to measure SPβ1 sera from 46 DS pregnancies and 117 normal control women matched for maternal age, gestational age, and len
Pregnancy-specific P,-glycoprotein, SP,, was measured in serum by competitive double antibody radioimmunoassay. Very low levels of SP, or SP,like activity were found in only 2 out of 85 sera from patients with cancer of the digestive tract, breast cancer, melanoma, and sarcoma, in 2 out of 11 sera f