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In Vitro Synthesis of IL-4 by Human CD4+ T Cells Requires Repeated Antigenic Stimulation

✍ Scribed by Jason D. Marshall; Yan Wen; John S. Abrams; Dale T. Umetsu


Book ID
112238789
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
649 KB
Volume
152
Category
Article
ISSN
0008-8749

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## Abstract IL‐10‐producing regulatory B cells have been identified in mice and shown to downregulate inflammation, making them potentially important for maintenance of tolerance. In this study, we isolated B cells from human blood and spleen, and showed that after a short period of __ex vivo__ sti