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In vitro study and semiempirical model for aerosol delivery control during mechanical ventilation

✍ Scribed by Laurent Vecellio; Claude Guérin; Daniel Grimbert; Michele De Monte; Patrice Diot


Publisher
Springer
Year
2005
Tongue
English
Weight
220 KB
Volume
31
Category
Article
ISSN
1432-1238

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A new generation drug delivery system, named the Microsealed Drug Delivery (MDD) system, was developed. Subcutaneous implantation of MDD's in rats for up to 129 days resulted in a constant release profile of desoxycorticosterone acetate. Three formulations were examined. An excellent i n uitro-in ui