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In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood

✍ Scribed by Birgit Paulsson; Agneta Rannug; Alistair P. Henderson; Bernard T. Golding; Margareta Törnqvist; Margareta Warholm


Book ID
116758917
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
190 KB
Volume
580
Category
Article
ISSN
1383-5718

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## Abstract The toxicity of dietary acrylamide (AA) depends on its biotransformation pathways, in which phase I cytochrome P‐450 enzymes transform AA into glycidamide. The phase II enzyme glutathione\___S__\_transferase (GST) catalyses the conjugation of AA with glutathione (GSH). GST induction by