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In vitro mutagenicity and cell transformation screening of caprolactam

✍ Scribed by Greene, Elliott J. ;Friedman, Marvin A. ;Sherrod, Julie A.


Publisher
Wiley (John Wiley & Sons)
Year
1979
Weight
417 KB
Volume
1
Category
Article
ISSN
0192-2521

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✦ Synopsis


Abstract

Caprolactam was tested for genetic activity in bacterial and mammalian screens. It was inactive in the following tests: a) Salmonella/microsome mutagenicity; b) Chinese hamster ovary cell mutagenicity (induction of 6‐thioguanine mutants); c) Enhancement of SA7 virus transformation of primary hamster embryo cells, when administered before or after virus, and; d) Chemical transformation of secondary hamster embryo cells.


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