In vitro models of human testicular germ-cell tumors
β Scribed by Franklin D. Gaylis; Elwin E. Fraley; David L. Bronson
- Book ID
- 104723232
- Publisher
- Springer-Verlag
- Year
- 1984
- Tongue
- English
- Weight
- 415 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0724-4983
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## BACKGROUND. There has been evidence of a higher incidence of testicular germ cell tumors (GCT) in human immunodeficiency virus (HlV)-seropositive men than in the non HIV-infected male population. Most authors recommend standard therapy for HIV-positive patients with GCT but the immunosuppressive
Testicular germ-cell tumors are relatively rare in childhood and adolescence, accounting for only 3.9% of all neoplasms. However, they have become a model for curable cancer. Furthermore, most of them have accurate serum markers [beta-human chorionic gonadotropin and alpha-fetoprotein], which provid