Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors
✍ Scribed by Nowak, Radoslawa; Sikora, Krzysztof; Piętas, Agnieszka; Skoneczna, Iwona; Chrapusta, Stanislaw J
- Book ID
- 110064066
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 132 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0950-9232
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Background. Hyperpentaploidy in testicular nonseminomatous germ cell tumors (TNSGCT) has been associated with progression of disease of patients who initially had TNSGCT in Stage I. Methods. The authors used flow cytometry to investigate the relationship between ploidy and the clinical behavior in
Testicular germ-cell tumors are relatively rare in childhood and adolescence, accounting for only 3.9% of all neoplasms. However, they have become a model for curable cancer. Furthermore, most of them have accurate serum markers [beta-human chorionic gonadotropin and alpha-fetoprotein], which provid