## Abstract The feasibility of performing highβresolution in vivo MRI on mouse spinal cord (SC) at 9.4 T magnetic field strength is demonstrated. The MR properties of the cord tissue were measured and the characteristics of water diffusion in the SC were quantified. The data indicate that the diffe
In vitro magnetic resonance microimaging of the spinal cord
β Scribed by C. Lemaire; E. G. Duncan; M. D. Solsberg; R. L. Armstrong
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 518 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0740-3194
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β¦ Synopsis
Abstract
A 2.0βT small animal imager equipped with 3 G/cm imaging gradient coils was used to obtain images of en bloc segments of the vertebral column containing the rat spinal cord and of a cadaveric human spinal cord. These images demonstrate the applicability of MR microβimaging techniques to the study of interesting problems in medicine and biology. Images of transverse sections of the spinal cord with inβplane resolution of better than 0.1 mm were obtained from slices 1 mm thick. The images of normal and injured rat spinal cord vividly show that spinal cord injury in the rat can be visualized using MRI techniques. The MR image of the cadaveric human spinal cord shows subanachroid gray and white matter structures. A comparison with a photomicrograph indicates that it is the superior contrast of the MR image that leads to increased conspicuity. Β© 1990 Academic Press, Inc.
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## Abstract Proton MR spectroscopy (^1^HβMRS) provides indices of neuronal damage in the central nervous system (CNS); however, it has not been extensively applied in the spinal cord. This work describes an optimized proton spectroscopy protocol for examination of the human cervical spinal cord. __