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In Vitro Interactions Between Model Proteins and Amyloid Inhibitors

✍ Scribed by Horvath, Istvan; Rosenbaum, Erik; Olofsson, Anders; Johansson, Lennart B.Å.; Almqvist, Fredrik; Wittung-Stafshede, Pernilla


Book ID
122587576
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
35 KB
Volume
100
Category
Article
ISSN
0006-3495

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## Abstract The conversion of soluble, nontoxic amyloid β‐protein (Aβ) to aggregated, toxic Aβ rich in β‐sheet structures is considered to be the key step in the development of Alzheimer's disease. Therefore, extensive studies have been carried out on the mechanisms involved in Aβ aggregation and t