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In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus

✍ Scribed by Henderson, M. C.; Miranda, C. L.; Stevens, J. F.; Deinzer, M. L.; Buhler, D. R.

Book ID
121697511
Publisher
Informa plc
Year
2000
Tongue
English
Weight
384 KB
Volume
30
Category
Article
ISSN
0049-8254

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Metabolism of xanthohumol and isoxanthoh
Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes
✍ Dejan Nikolic; Yongmei Li; Lucas R. Chadwick; Guido F. Pauli; Richard B. van Bre πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 240 KB

## Abstract The female flowers of hops (__Humulus lupulus__ L.) used to flavor beer contain the prenylated flavonoids xanthohumol (XN) and isoxanthohumol (IX). IX is moderately estrogenic __in vitro__ and XN has pharmacological properties that might make it useful as a cancer chemopreventive agent.